Classifying CDI

ACG Guidelines

Non Severe CDI:

We recommend the following criteria, which are predictive of unfavorable outcomes, be used to classify severe C. difficile infection at the time of diagnosis: white blood cell (WBC) ≥15,000 cells/mm3 or serum creatinine >1.5 mg/dL.

We recommend defining fulminant infection as patients meeting criteria for severe C. difficile infection plus presence of hypotension or shock or ileus or megacolon.